Mitochondrial Dysfunction Caused by Drugs and Environmental Toxicants
Yvonne Will и James Dykens
Тип: PDF книга
Жанр: Зарубежная образовательная литература
Язык: на английском языке
Издательство: John Wiley & Sons Limited
Дата публикации: 25.04.2024
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О книге: Developed as a one-stop reference source for drug safety and toxicology professionals, this book explains why mitochondrial failure is a crucial step in drug toxicity and how it can be avoided. • Covers both basic science and applied technology / methods • Allows readers to understand the basis of mitochondrial function, the preclinical assessments used, and what they reveal about drug effects • Contains both in vitro and in vivo methods for analysis, including practical screening approaches for drug discovery and development • Adds coverage about mitochondrial toxicity underlying organ injury, clinical reports on drug classes, and discussion of environmental toxicants affecting mitochondria